Magnets kill cancer cells in lab

Belfast Telegraph

A magnetic method of killing cancer cells has been developed by scientists in South Korea.
The technique uses a magnetic field to flip a “self-destruct” switch in tumours.

Researchers have demonstrated that the process works in bowel cancer cells and living laboratory fish. Programmed cell death, or apoptosis, is one of the body’s ways of getting rid of old, faulty or infected cells.

In response to certain signals, the doomed cell shrinks and breaks into fragments. These are then engulfed and consumed by amoeba-like immune cells.

Often in cancer, apoptosis fails and cells are allowed to keep dividing uncontrollably.

The magnetic therapy involves creating tiny iron nanoparticles attached to antibodies which bind to “receptor” molecules on tumour cells. When the magnetic field is applied, the molecules cluster together, automatically triggering the “death signal” that sets off apoptosis.

In laboratory experiments, bowel cancer cells were exposed to the nanoparticles and placed between two magnets. The cells were designed to light up green to signal that apoptopic clustering was taking place.

More than half the exposed cells were destroyed by magnetic activation, whereas no untreated cells were affected. In another experiment, magnetically-induced apoptosis in zebra fish caused the creatures to grow abnormal tails.

Details of the research, led by Professor Jinwoo Cheon, from Yonsei University in Seoul, appear in the journal Nature Materials.

The scientists wrote: “We have demonstrated that apoptosis signalling can be turned on in-vitro (in the laboratory) and in a zebra fish in-vivo (living) model by using a magnetic switch. Our magnetic switch may be broadly applicable to any type of surface membrane receptors that exhibit cellular functions on clustering.”

Related:  Cancer cells can be burned up with magnetic pulses

Scientists Recommend Dangerous Antipsychotic Drugs to Treat Cancer

Activist Post

The Obama administration recently announced that the US government will assist pharmaceutical corporations in finding prescription drugs to treat new diseases.

The focus of this collaboration will identify new uses for drugs that have already been approved by the Food and Drug Administration (FDA).

“We need to speed the pace at which we are turning discoveries into better health outcomes,” said Dr. Francis Collins, of the National Institutes of Health (NIH). “NIH looks forward to working with our partners in industry and academia to tackle an urgent need that is beyond the scope of any one organization or sector.”

Obama signed Executive Order (EO), Establishing the National Prevention, Health Promotion and Public Health Council in 2010.

Now the medical journal Cell has published a research paper on using an extremely dangerous psychotropic pharmaceutical to treat cancer; one that has traditionally been used to treat schizophrenia.

Scientists are claiming that according to their extensive research, which consisted of analyzing thousands of different drugs to determine if they possessed anti-cancer effects, it is Thiroridazine — a “last resort” drug for schizophrenics — that is now purported to kill cancer stem cells.

Thioridazine is expected to be used to select and eradicate cancer stem cells that are found in leukemia and several other cancers such as breast, blood, brain, prostate, ovarian, lung and gastrointestinal.

Scientists claim that this hazardous pharmaceutical can be administered in cancer therapies, without the health-threatening side effects of current drugs on the market. It is being advertised as an alternative to chemotherapy and radiation.

A robotic stem cell screening system was devised by the research team to siphon through large amounts of drugs and previously unpublished data and drugs that are available on the market today. Thousands of chemical compounds were screened for potential effects on specifically breast cancer and leukemia.

“We discovered the drug by creating a new way of looking at different chemicals,” said Mick Bhatia, the principal investigator for the study and scientific director of McMaster’s Stem Cell and Cancer Research Institute in the Michael G. DeGroote School of Medicine.

In order to do that, we have to put cancer stem cells in a dish, but also have normal stem cells to also test the compounds. We were able to do this with a robotic system, fully automated, that allowed us to go through 10 or 15 compounds [at first]. Now we can do this with thousands of compounds, eventually arriving at this drug that doesn’t do anything to normal stem cells, but kills cancer stem cells.

The unusual aspect of our finding is the way this human-ready drug actually kills cancer stem cells; by changing them into cells that are non-cancerous.

The praise Thioridazine is receiving omits the dangerous effects that this drug causes in humans.

Vomiting
Seizures
Ulcers
Urinary tract infections
Swelling
Slowed movements
Inability to produce facial expressions
Parkinson’s disease
Irregular heart beat
Sudden death

Thioridazine is classified as a conventional antipsychotic. Its prime function is to reduce the brain’s ability to process excitement; effectively rendering the patient docile and even-tempered.

There is a strong possibility of committing suicide while on this drug.

Bhatia’s study asserts that this discovery could inspire a new frontier in cancer therapies. He stated that there are an estimated 12 existing drugs that pose a “good potential for the same response.”

The researchers are not stopping with Thioridazine; they are moving onto other possible uses for already approved drugs.

Bhatia’s team is anxious to begin human trials with plans to use this pharmaceutical on leukemia patients. By studying patients whose cancer is in remission, the researchers hope to find that thioridazine will prevent a multitude of cancers.

Currently, the vitamin industries, by order of the Codex Alimentarius (CA) are being attacked by the US government to justify the force outlawing of natural medicine use. The CA is a creation of the World Health Organization (WHO) and the Food and Agriculture Organization of the United Nations.

The findings of this study are just the first of many “new uses” that the pharmaceutical industry will “discover” in order to utilize antipsychotic drugs to treat major diseases.

With the support of the Obama administration, soon we may all be on some kind of psychotropic drug.